#151061

Anti-Cdc13 [6F11/2]

Cat. #151061

Anti-Cdc13 [6F11/2]

Cat. #: 151061

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Cell-division cycle protein 13 (cdc13)

Class: Monoclonal

Application: WB ; IHC ; IP ; WB

Reactivity: Schizosaccharomyces pombe

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Jacqueline Hayles

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Cdc13 [6F11/2]
  • Alternate name: Cell division control protein 13; YDL22C
  • Clone: 6F11/2
  • Tool type ecom: Antibodies
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Schizosaccharomyces pombe
  • Host: Mouse
  • Application: WB ; IHC ; IP ; WB
  • Description: 6F11/2 can be used for detecting Cdc13 and associated Cdk1 kinase activation.
  • Immunogen: Full length cdc13
  • Isotype: IgG2a
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: Cell-division cycle protein 13 (cdc13)
  • Target background: Cdc13 is a fission yeast (S. pombe) B-type M-phase cyclin. Cdc13 binds to Cdk1 (cdc2), and the resulting Cdk1-Cdc13 complex controls the G2/M transition of the cell cycle.

Applications

  • Application: WB ; IHC ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Rothe et al. 2017. J Cell Sci. 130(23):4028-4037. PMID: 29046339.
  • Koch et al. 2012. ACS Chem Biol. 7(4):723-31. PMID: 22264160.
  • A chemical genetic approach for covalent inhibition of analogue-sensitive aurora kinase.
  • Okuzaki et al. 2010. Cell Cycle. 9(18):3751-60. PMID: 20855961.
  • Spo5 phosphorylation is essential for its own timely degradation and for successful meiosis in Schizosaccharomyces pombe.
  • Decottignies et al. 2001. J Cell Sci. 114(Pt 14):2627-40. PMID: 11683390.
  • In vivo localisation of fission yeast cyclin-dependent kinase cdc2p and cyclin B cdc13p during mitosis and meiosis.