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#151302

Anti-Cdc20 [BA8]

Cat. #151302

Anti-Cdc20 [BA8]

Cat. #: 151302

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Cell division cycle protein 20 (cdc20)

Class: Monoclonal

Application: ELISA ; FACS ; WB

Reactivity: Xenopus laevis

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Julian Gannon

Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Cdc20 [BA8]
  • Alternate name: APC/C activator protein CDC2; Cell division control protein 2; YGL116W; Cell Division Cycle 2; P55CDC; CDC2 Cell Division Cycle 2; BA276H19.3; CDC2A
  • Research fields: Biochemistry;Cell biology
  • Clone: BA8
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Xenopus laevis
  • Host: Mouse
  • Application: ELISA ; FACS ; WB
  • Description: Fizzy protein (cdc20) is associated with the activation of the anaphase-promoting complex (APC) at the onset of anaphase.
  • Immunogen: Peptide from the carboxy terminus of the protein.
  • Isotype: IgG2a
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: Cell division cycle protein 20 (cdc20)
  • Target background: Fizzy protein (cdc20) is associated with the activation of the anaphase-promoting complex (APC) at the onset of anaphase.

Applications

  • Application: ELISA ; FACS ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Dry ice

References

  • Ohe et al. 2010. Mol Biol Cell. 21(6):905-13. PMID: 20089832.
  • Emi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail.
  • Sironi et al. 2001. EMBO J. 20(22):6371-82. PMID: 11707408.
  • Mad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.
  • Lorca et al. 1998. EMBO J. 17(13):3565-75. PMID: 9649427.
  • Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts.

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