#153400

Anti-Mucin 3 [1143/B7]

Cat. #153400

Anti-Mucin 3 [1143/B7]

Cat. #: 153400

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: MUC3

Class: Monoclonal

Application: ELISA ; IHC

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Mike Price

Institute: University of Nottingham

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Mucin 3 [1143/B7]
  • Alternate name: MUC3A; Mucin 3; Intestinal mucin-3A
  • Cancer: Digestive / Gastrointestinal cancer
  • Cancers detailed: Colorectal
  • Research fields: Cancer;Cell biology;Genetics
  • Clone: 1143/B7
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 22 kDa
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC
  • Description: Mucin 3 (MUC3) is a glycoprotein. Distributed in colon and rectum, and to a lesser extent in breast, lung and salivary gland tissues. Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling.
  • Immunogen: MUC3 tandem repeat peptide
  • Isotype: IgG2a

Target Details

  • Target: MUC3
  • Molecular weight: 22 kDa
  • Target background: Mucin 3 (MUC3) is a glycoprotein. Distributed in colon and rectum, and to a lesser extent in breast, lung and salivary gland tissues. Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling.

Applications

  • Application: ELISA ; IHC

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Rossi et al. 2012. Histopathology. 60(7):1133-43. PMID: 22348416.
  • MUC5AC, cytokeratin 20 and HER2 expression and K-RAS mutations within mucinogenic growth in congenital pulmonary airway malformations.
  • Teshima et al. 2011. J Anat. 219(3):410-7. PMID: 21679184.
  • Development of human minor salivary glands: expression of mucins according to stage of morphogenesis.
  • Louis et al. 2006. J Cell Biochem. 99(6):1616-27. PMID: 16823775.
  • Selective induction of mucin-3 by hypoxia in intestinal epithelia.