Cat. #153400
Anti-Mucin 3 [1143/B7]
Cat. #: 153400
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: MUC3
Class: Monoclonal
Application: ELISA ; IHC
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Mike Price
Institute: University of Nottingham
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Mucin 3 [1143/B7]
- Alternate name: MUC3A; Mucin 3; Intestinal mucin-3A
- Cancer: Digestive / Gastrointestinal cancer
- Cancers detailed: Colorectal
- Research fields: Cancer;Cell biology;Genetics
- Clone: 1143/B7
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 22 kDa
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC
- Description: Mucin 3 (MUC3) is a glycoprotein. Distributed in colon and rectum, and to a lesser extent in breast, lung and salivary gland tissues. Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling.
- Immunogen: MUC3 tandem repeat peptide
- Isotype: IgG2a
Target Details
- Target: MUC3
- Molecular weight: 22 kDa
- Target background: Mucin 3 (MUC3) is a glycoprotein. Distributed in colon and rectum, and to a lesser extent in breast, lung and salivary gland tissues. Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling.
Applications
- Application: ELISA ; IHC
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Rossi et al. 2012. Histopathology. 60(7):1133-43. PMID: 22348416.
- MUC5AC, cytokeratin 20 and HER2 expression and K-RAS mutations within mucinogenic growth in congenital pulmonary airway malformations.
- Teshima et al. 2011. J Anat. 219(3):410-7. PMID: 21679184.
- Development of human minor salivary glands: expression of mucins according to stage of morphogenesis.
- Louis et al. 2006. J Cell Biochem. 99(6):1616-27. PMID: 16823775.
- Selective induction of mucin-3 by hypoxia in intestinal epithelia.
