Cat. #155244
Anti-IAb +Ea peptide [YAe]
Cat. #: 155244
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: MHC Class II (IA/IE)
Class: Monoclonal
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Yale University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-IAb +Ea peptide [YAe]
- Research fields: Immunology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Description: Monoclonal antibody which binds YAe antigen on B cells and antigen presenting cells. Background and Research Application This YAe antibody reacts with a class II major histocompatibility complex (MHC) self Ea peptide (peptide 52-68) bound to I-Ab molecules. The YAe antibody binds to an epitope expressed on a subset of class II I-Ab molecules in strains that also express class II I-Eb. This epitope is found on peripheral B cells and on cells in the thymic medulla, but not thymic cortical epit...
- Immunogen: P14483
- Immunogen uniprot id: P14483
Target Details
- Target: MHC Class II (IA/IE)
- Target background: Monoclonal antibody which binds YAe antigen on B cells and antigen presenting cells. Background and Research Application This YAe antibody reacts with a class II major histocompatibility complex (MHC) self Ea peptide (peptide 52-68) bound to I-Ab molecules. The YAe antibody binds to an epitope expressed on a subset of class II I-Ab molecules in strains that also express class II I-Eb. This epitope is found on peripheral B cells and on cells in the thymic medulla, but not thymic cortical epit...
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
- Shipping conditions: Dry ice
References
- Bonacina et al. 2018. Nat Commun. 9(1):3083. PMID: 30082772.
- Rouhani et al. 2015. Nat Commun. 6:6771. PMID: 25857745.
- Michelet et al. 2015. J Immunol. 194(5):2079-88. PMID: 25637027.
- Murphy et al. 1989. Nature. 338(6218):765-8. PMID: 2469959.
