Cat. #152122
Anti-Cytochrome P450 39A1 [M30P6D6]
Cat. #: 152122
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: CYP39A1-Cytochrome P450, family 39, subfamily A, polypeptide 1.
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Cytochrome P450 39A1 [M30P6D6]
- Research fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
- Clone: M30P6D6
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: CYP39A1 (cytochrome P450, family 39, subfamily A, polypeptide 1), also known as 24- hydroxycholesterol 7-ÄÂ?-hydroxylase localises to both the microsome and the endoplasmic reticulum. Using heme groups as cofactors, CYP39A1 is involved in the bile acid metabolism and is specifically expressed in liver.
- Immunogen: Ovalbumin-conjugated synthetic peptide CRIEYKQRI (C-terminal sequence).
- Isotype: IgG3 kappa
- Myeloma used: P3X63Ag8.653
- Recommended controls: IHC: formalin-fixed, paraffin-embedded human liver sections. WB: pooled human liver microsomes.
Target Details
- Target: CYP39A1-Cytochrome P450, family 39, subfamily A, polypeptide 1.
- Tissue cell line specificity: IHC: formalin-fixed, paraffin-embedded human liver sections. WB: pooled human liver microsomes.
- Target background: CYP39A1 (cytochrome P450, family 39, subfamily A, polypeptide 1), also known as 24- hydroxycholesterol 7-a-hydroxylase localises to both the microsome and the endoplasmic reticulum. Using heme groups as cofactors, CYP39A1 is involved in the bile acid metabolism and is specifically expressed in liver.
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer.
- Swan et al. 2016. Oncotarget. :. PMID: 27341022.
