#152699

Anti-Cytochrome P450 1B1 [5E2]

Cat. #152699

Anti-Cytochrome P450 1B1 [5E2]

Cat. #: 152699

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Cytochrome P450, Family 1, Subfamily B, Polypeptide 1, CYP1B1

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human ; Mouse ; Rat

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Cytochrome P450 1B1 [5E2]
  • Research fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
  • Clone: 500
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 52 kDa
  • Strain: Balb/c
  • Reactivity: Human ; Mouse ; Rat
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.Participates in the metabolism of an as-yet-unknown biologically active molecule that is a participant in eye development. CYP1B1 is upregulated in tumour cells and is a therapeutic target
  • Immunogen: Ovalbumin-conjugated synthetic peptide - PENFDPARFLDKDGL
  • Isotype: IgG1 kappa
  • Recommended controls: IHC: formalin-fixed, paraffin-embedded ovarian cancer sections; Western Blot: Recombinant human CYP1B1 expressed in lymphoblast microsomes

Target Details

  • Target: Cytochrome P450, Family 1, Subfamily B, Polypeptide 1, CYP1B1
  • Molecular weight: 52 kDa
  • Tissue cell line specificity: IHC: formalin-fixed, paraffin-embedded ovarian cancer sections; Western Blot: Recombinant human CYP1B1 expressed in lymphoblast microsomes
  • Target background: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.Participates in the metabolism of an as-yet-unknown biologically active molecule that is a participant in eye development. CYP1B1 is upregulated in tumour cells and is a therapeutic target

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

Related Tools

  • Related tools: Anti-Cytochrome P450 1B1 [V96]

References

  • McFadyen et al. 1999. J Histochem Cytochem. 47(11):1457-64. PMID: 10544218.
  • Immunohistochemical localization of cytochrome P450 CYP1B1 in breast cancer with monoclonal antibodies specific for CYP1B1.