![Western blot on recombinant protein using anti-Cytochrome P450 1B1 [5E2]. Dilution refers to tissue culture supernatant.](https://cancertools.org/wp-content/uploads/cb3100be-0507-4ce1-8042-20dc8409df14.jpg)
Cat. #152699
Anti-Cytochrome P450 1B1 [5E2]
Cat. #: 152699
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Cytochrome P450, Family 1, Subfamily B, Polypeptide 1, CYP1B1
Class: Monoclonal
Application: ELISA ; IHC ; WB
Reactivity: Human ; Mouse ; Rat
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Ayham Alnabulsi
Institute: Vertebrate Antibodies Limited
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Cytochrome P450 1B1 [5E2]
- Research fields: Cancer;Cell signaling and signal transduction;Metabolism;Tissue-specific biology
- Clone: 500
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 52 kDa
- Strain: Balb/c
- Reactivity: Human ; Mouse ; Rat
- Host: Mouse
- Application: ELISA ; IHC ; WB
- Description: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.Participates in the metabolism of an as-yet-unknown biologically active molecule that is a participant in eye development. CYP1B1 is upregulated in tumour cells and is a therapeutic target
- Immunogen: Ovalbumin-conjugated synthetic peptide - PENFDPARFLDKDGL
- Isotype: IgG1 kappa
- Recommended controls: IHC: formalin-fixed, paraffin-embedded ovarian cancer sections; Western Blot: Recombinant human CYP1B1 expressed in lymphoblast microsomes
Target Details
- Target: Cytochrome P450, Family 1, Subfamily B, Polypeptide 1, CYP1B1
- Molecular weight: 52 kDa
- Tissue cell line specificity: IHC: formalin-fixed, paraffin-embedded ovarian cancer sections; Western Blot: Recombinant human CYP1B1 expressed in lymphoblast microsomes
- Target background: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.Participates in the metabolism of an as-yet-unknown biologically active molecule that is a participant in eye development. CYP1B1 is upregulated in tumour cells and is a therapeutic target
Applications
- Application: ELISA ; IHC ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
Related Tools
- Related tools: Anti-Cytochrome P450 1B1 [V96]
References
- McFadyen et al. 1999. J Histochem Cytochem. 47(11):1457-64. PMID: 10544218.
- Immunohistochemical localization of cytochrome P450 CYP1B1 in breast cancer with monoclonal antibodies specific for CYP1B1.
