Cat. #160518
CS-5c Bcr-Abl and Btk small molecule kinase inhibitors
Cat. #: 160518
Sub-type: Inhibitor
Availability: Please enquire for quantities and pricing
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Cristian Salas
Institute: Pontificia Universidad Catolica de Chile
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Tool name: CS-5c Bcr-Abl and Btk small molecule kinase inhibitors
- Cancer: Blood cancer
- Cancers detailed: Leukemia
- Research fields: Cancer;Drug development;Other
- Molecular formula: C26H29FN8
- Tool sub type: Inhibitor
- Primary target: Bcr-Abl and Btk kinases
- Description: This compound inhibits in nanomolar scale for Bcr-Abl (40 nM) and sub-micromolar scale for Btk kinases (0,58
- Purpose: Inhibitor
- Iupac: 9-(Cyclopropylmethyl)-N6-(3-fluorophenyl)-N2-(4-(4-methylpiperazin-1-yl)phenyl)-9H-purine-2,6-diamine
- Molecular weight: 472.5605
- Solubility: DMSO
Handling
- Purity: 472.5605 g/mol
- Storage conditions: Away from UV light
- Shipping conditions: Dry Ice
Target Details
- Primary target: Bcr-Abl and Btk kinases
Related Tools
- Related tools: CS-5d Bcr-Abl and Btk small molecule kinase inhibitors
References
- Bertrand et al. 2020. Bioorg Chem. 94:103361. PMID: 31699386.
