#158320

PL1 peptide

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Cat. #158320

PL1 peptide

Cat. #: 158320

Sub-type: Synthetic Peptide

Availability: Please enquire for quantities and pricing

Target: Oncofetal fibronectin extra domain-B (FN-EDB) and tenascin-C C domain (TNC-C). Relevant disease: Cancer

Function: Marker

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

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Contributor

Inventor: Tambet Teesalu ; Prakash Lingasamy

Institute: University of Tartu

Tool Details
Handling
Target Details
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Tool name: PL1 peptide
  • Alternate name: PL1, FN-EDB and TNC-C binding protein
  • Research fields: Cancer;Cell biology
  • Tool sub type: Synthetic Peptide
  • Sequence: PPRRGLIKLKTS
  • Cellular tissue localisation: Extracellular matrix
  • Target: Oncofetal fibronectin extra domain-B (FN-EDB) and tenascin-C C domain (TNC-C). Relevant disease: Cancer
  • Description: PL1 peptide is a short binding peptide which interacts with oncofetal fibronectin extra domain-B (FN-EDB) and tenascin-C C domain (TNC-C) which are both extracellular matrix proteins present in a tumour microenvironment. The targets of PL1 are nearly absent in normal adult tissues making them indicative of solid tumour tissues. It has been shown that this dual-targeted peptide can be used for robust and specific delivery of imaging agents and therapeutic payloads to solid tumours.
  • Function: Marker
  • Expression system: Synthetic

Handling

  • Shipping conditions: Dry Ice

Target Details

  • Target: Oncofetal fibronectin extra domain-B (FN-EDB) and tenascin-C C domain (TNC-C). Relevant disease: Cancer

Related Tools

  • Related tools: PL2 Peptide ; PL3 Peptide

References

  • Bi-specific tenascin-C and fibronectin targeted peptide for solid tumor delivery

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