#154268

Gulf War Illness Rat

Cat. #154268

Gulf War Illness Rat

Cat. #: 154268

Sub-type: Mouse

Availability: 8-10 weeks

Disease: Gulf War Illness

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Laxmikant Deshpande

Institute: Virginia Commonwealth University

Tool Details
Target Details
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Tool name: Gulf War Illness Rat
  • Tool sub type: Mouse
  • Disease: Gulf War Illness
  • Description: Repeated low-dose organophosphate diisopropyl fluorophosphate (DFP) exposre leads to the development of depression and cognitive impairment in a rat model of Gulf War Illness
  • Phenotype: Gulf War Illness
  • Zygosity: unknown
  • Production details: Rats were injected s.c. with 400 Âľg/kg DFP once-daily for 5 days
  • Additional notes: Male Sprague-Dawley Rats

Target Details

  • Target: acetylcholinesterase

References

  • Phillips et al. 2019. Toxicol Sci. 169(2):567-578. PMID: 30859209.
  • Targeting Intracellular Calcium Stores Alleviates Neurological Morbidities in a DFP-Based Rat Model of Gulf War Illness.
  • Phillips et al. 2018. Mil Med. 183(suppl_1):552-555. PMID: 29635560.
  • Chronic Neurological Morbidities and Elevated Hippocampal Calcium Levels in a DFP-Based Rat Model of Gulf War Illness.
  • Phillips et al. 2016. Neurotoxicology. 52:127-33. PMID: 26619911.
  • Repeated low-dose organophosphate DFP exposure leads to the development of depression and cognitive impairment in a rat model of Gulf War Illness.