Cat. #161778
TOV-2929D cell line
Cat. #: 161778
Availability: 8-10 weeks
Organism: Human
Tissue: Derived from solid tumor of patient diagnosed with high-grade serous ovarian cancer at specific time points at diagnosis and relapse
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Anne-Marie Mes-Masson and Diane Provencher
Institute: Centre Hospitalier de Luniversité de Montréal
Primary Citation: Sauriol A et al. 2020. Cancers. 12(8):2222. PMID: 32784519
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: TOV-2929D cell line
- Alternate name: TOV-2929D
- Cancer: Gynaecologic cancer
- Research fields: Cancer
- Organism: Human
- Gender: Female
- Tissue: Derived from solid tumor of patient diagnosed with high-grade serous ovarian cancer at specific time points at diagnosis and relapse
- Donor: Grade 3 Stage IIIC; Mutations: TP53 Exon 7; Pre-treatment for ovarian cancer/ colon cancer 5 years before
- Morphology: Characteristic flattened cobblestone-like appearance. Formed compact flat discs rather than spherical spheroids.
- Growth properties: Adherent
- Crispr: No
- Receptors of note: No
- Description: Epithelial ovarian cancer cell lines spontaneously derived from solid tumor of patient diagnosed with high-grade serous ovarian cancer. Sample taken from solid tissue of the ovary, specifically derived from samples of the right ovary
- Production details: Established using the Scrape method where tumor tissue was scraped into a 100mm plate with complete OSE medium and maintained for 40 days with medium replaced weekly.
- Additional notes: Patient 2929 was age 77 at time of diagnosis with prior history of colorectal cancer. Patient was chemonaive at the time of sampling and sampling took place in 2006.
Handling
- Growth medium: OSE medium contains 10% FBS, 0.5ug/mL amphotericin B and 50 ug/mL gentamicin
- Temperature: 37° C
- Atmosphere: Low oxygen conditions of 7% O2 and 5% CO2
- Cultured in antibiotics: Amphotericin B and Gentamicin
References
- Gaia-Oltean et al. 2021. Exp Ther Med. 21(3):243. PMID: 33603851 Canals Hernaez et al. 2020. J Immunother Cancer. 8(2):e001128. PMID: 33243933 Borzdzi?owska et al. 2022. Biomedicines. 11
- 10(5):1116. PMID: 35625852 Meng et al. 2023. J Anim Sci. 3
- 101:skad215. PMID: 37351870 Koni et al. 2020. Int J Mol Sci. 18
- 21(20):7697. PMID: 33080952
