TOV-2414 cell line

Cat. #161776

TOV-2414 cell line

Cat. #: 161776

Organism: Human

Tissue: Derived from solid tumor from patient of mucinous carcinoma


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Inventor: Anne-Marie Mes-Masson and Diane Provencher

Institute: Centre Hospitalier de L’université de Montréal

Primary Citation: Sauriol A et al. 2020. Cancers. 12(8):2222. PMID: 32784519

Tool Details

Tool Details


  • Name: TOV-2414 cell line
  • Alternate name: TOV-2414
  • Organism: Human
  • Gender: Female
  • Tissue: Derived from solid tumor from patient of mucinous carcinoma
  • Donor: Grade 1 – Stage IIIC; Mutations: K-RAS2; Pre-treatment
  • Morphology: Stretched-like morphology
  • Growth properties: Adherent
  • Crispr: No
  • Receptors of note: No
  • Description: Epithelial ovarian cancer cell line derived from solid tumor from patient of mucinous carcinoma who was chemonaive at the time of sampling. Cell line produces tumors in mice upon SC injection
  • Production details: Established using the Scrape method where tumor tissue was scraped into a 100mm plate with complete OSE medium and maintained for 40 days with medium replaced weekly.
  • Additional notes: Patient 2414 was diagnosed at age 63 and had no prior cancer history. Site of sampling was the ovary and year of sampling was 2005.


  • Growth medium: OSE medium contains 10% FBS, 0.5ug/mL amphotericin B and 50 ug/mL gentamicin
  • Temperature: 37° C
  • Atmosphere: Low oxygen conditions of 7% O2 and 5% CO2
  • Cultured in antibiotics: Amphotericin B and Gentamicin


  • Gaia-Oltean et al. 2021. Exp Ther Med. 21(3):243. PMID: 33603851 Canals Hernaez et al. 2020. J Immunother Cancer. 8(2):e001128. PMID: 33243933 Borzdzi?owska et al. 2022. Biomedicines. 11
  • 10(5):1116. PMID: 35625852 Meng et al. 2023. J Anim Sci. 3
  • 101:skad215. PMID: 37351870 Koni et al. 2020. Int J Mol Sci. 18
  • 21(20):7697. PMID: 33080952