Cat. #161923
SK-UT-1 Cell Line
Cat. #: 161923
Availability: 8-10 weeks
Organism: Human
Tissue: Uterus
Model: Tumourigenic
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Lloyd J. Old, Germaine Trempe
Institute: Memorial Sloan-Kettering Cancer Center (MSK)
Primary Citation: Fogh et al. 1977. Journal of the National Cancer Institute. 59: 221-226. PMID: 327080.
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: SK-UT-1 Cell Line
- Cancer: Genitourinary cancer
- Cancers detailed: Genitourinary cancer
- Organism: Human
- Gender: Female
- Tissue: Uterus
- Donor: This cell line was established in 1972 from a 75-year-old Caucasian female with a uterine mixed mesodermal tumor consistent with leiomyosarcoma grade III.
- Morphology: Epithelial
- Growth properties: Adherent
- Model: Tumourigenic
- Model description: Tumourigenic in nude mice
- Products or characteristics of interest: Karyotype: (P8) hypodiploid to hyperdiploid. Isoenzymes: AK-1, 1; ES-D, 1; G6PD, B; Me-2, 1-2; PGM1, 1; PGM3, 1
- Description: This cell line has little or no phosphorylated retinoblastoma protein compared to the SK-UT-1B cells. SK-UT-1 cells are capable of forming tumours when inoculated in immunocompromised mice.
- Application: 3D cell culture
- Biosafety level: 1
- Additional notes: The cells form spindle cell sarcomas.
Target Details
- Target: Antigen expression: Blood Type B; Rh+
Applications
- Application: 3D cell culture
Handling
- Growth medium: EMEM supplemented with FBS to a final concentration of 10%; formulated for use with a 5% CO2 in air atmosphere
- Temperature: 37° C
- Atmosphere: 5% CO2 in air
- Shipping conditions: Dry Ice
- Storage medium: Complete growth medium supplemented with 5% (v/v) DMSO
- Storage conditions: Vapor phase of liquid nitrogen
- Str profiling: Amelogenin: XCSF1PO: 10,11D13S317: 13D16S539: 13,14D5S818: 10,11D7S820: 9,10TH01: 7TPOX: 8vWA: 15,16D3S1358: 15,16D21S11: 29,32.2D18S51: 11,16Penta_E: 17Penta_D: 11,14,15D8S1179: 13,15FGA: 22,24D19S433: 12,13D2S1338: 18,19,21
References
- Ganiatsas et al. 2001. Oncogene. 20: 3641-50. PMID: 11439327.
- Li et al. 2013. International Journal of Gynecological Cancer. 23: 803-808. PMID: 23532091.
