#162039

Melan-sut2 cell line

Cat. #162039

Melan-sut2 cell line

Cat. #: 162039

Organism: Mouse

Tissue: Skin

Disease: Non-cancer

Model: Immortalised non-cancerous cell lines

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Elena Sviderskaya

Institute: St. George's University London

Tool Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Melan-sut2 cell line
  • Organism: Mouse
  • Tissue: Skin
  • Disease: Non-cancer
  • Morphology: Small, oval-fusiform
  • Model: Immortalised non-cancerous cell lines
  • Description: The melan-sut1, -sut2 and -sut3 cell lines are immortal melanocytes derived from Slc7a11sut/Slc7a11sut Ink4aArf -/- B6/C3H/HeSnJ mice. The Slc7a11 locus encodes a cysteine antiporter and regulates pheomelanogenesis. The sut mouse (Slc7a11 mutant) reduces pheomelanogenesis. In humans SLC7A11 expression may be elevated in melanoma patients. These cells may be useful for the study of pigment cell biology and for the role of Slc7a11 in melanoma.
  • Application: Melanocyte cell biology

Applications

  • Application: Melanocyte cell biology

Handling

  • Storage conditions: liquid N2