#162036

Melan-si4 cell line

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Cat. #162036

Melan-si4 cell line

Cat. #: 162036

Organism: Mouse

Tissue: Skin

Disease: Non-cancer

Model: Immortalised non-cancerous cell lines

£575.00

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Contributor

Inventor: Elena Sviderskaya

Institute: St. George's University London

Tool Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Melan-si4 cell line
  • Organism: Mouse
  • Tissue: Skin
  • Disease: Non-cancer
  • Morphology: Small, oval-fusiform
  • Model: Immortalised non-cancerous cell lines
  • Description: The melan-si3, -si-4 and -si5 cell lines are immortal melanocytes derived from Sisi/Sisi, Ink4a-Arf -/- C57BL/6J mice. The silver locus (si) encodes Pmel, a pigment-cell specific protein that forms functional amyloid within melanosomes to enable melanin deposition. These melanocytes retain pigmentation, but melanosomes do not contain Pmel fibrils, thus melanosomes are generally circular in shape. These cells may be useful for the study of early melanosome biogenesis.
  • Application: Melanocyte cell biology

Applications

  • Application: Melanocyte cell biology

Handling

  • Storage conditions: liquid N2