Cat. #161927
Caov-4 Cell Line
Cat. #: 161927
Availability: 8-10 weeks
Tissue: Fallopian tube
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Jorgen Fogh
Institute: Memorial Sloan-Kettering Cancer Center (MSK)
Primary Citation: Fogh et al. 1977. Journal of the National Cancer Institute. 58: 209-214. PMID: 833871.
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Caov-4 Cell Line
- Cancer: Adenocarcinoma;Gynaecologic cancer
- Gender: Female
- Tissue: Fallopian tube
- Donor: This cell line was established from a metastatic site (fallopian tube) in a 45-year-old Caucasian female with adenocarcinoma of the ovary.
- Morphology: Epithelial
- Growth properties: Adherent
- Products or characteristics of interest: Karyotype: (P5) hypotriploid and hypertetraploid with abnormalities including breaks, dicentrics, minute chromatin bodies, fragmentations, secondary constrictions and large subtelocentric and submetacentric markers. Isoenzymes: AK-1, 1; ES-D, 2; G6PD, B; GLO-I, 1-2; Me-2, 2; PGM1, 1-2; PGM3, 2
- Description: Ovarian cancer cell line with epithelial morphology taken from the ovaries of a 45 yr/old female. Cells grow in adherent culture, harbour a loss-of-function mutation in the p53 gene, and are sensitive to Cisplatin.
- Application: 3D cell culture, Cancer research
- Biosafety level: 1
- Additional notes: Caov-4 cells may grow exceedingly slow and may take as long as 4 weeks between subcultures.
Applications
- Application: 3D cell culture, Cancer research
Handling
- Growth medium: Leibovitz's L-15 Medium with fetal bovine serum to a final concentration of 20%.
- Temperature: 37° C
- Atmosphere: 100% air
- Shipping conditions: Dry Ice
- Storage medium: Complete growth medium supplemented with an additional 40% fetal bovine serum and 10% (v/v) DMSO
- Str profiling: D3S1358: 16,17TH01: 6,9.3D21S11: 28,33.2D18S51: 21Penta_E: 12,13D5S818: 11,13D13S317: 12,14D7S820: 8,10D16S539: 9,11CSF1PO: 10,11Penta_D: 9,10Amelogenin: XvWA: 16,17D8S1179: 12,15TPOX: 8,9FGA: 22D19S433: 11,12D2S1338: 17,20
References
- Yaginuma et al. 1997. Experimental Cell Research. 233:2-9. PMID: 9194486.
