#154235

2C4 cell line

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Cat. #154235

2C4 cell line

Cat. #: 154235

Sub-type: Continuous

Unit size: 1x10^6 cells / vial

Availability: 3-4 weeks

Organism: Human

Disease: Cancer

£575.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: George Stark ; Ian Kerr

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: 2C4 cell line
  • Cancer: Sarcoma
  • Cancers detailed: Fibrosarcoma
  • Research fields: Cancer;Cell signaling and signal transduction;Immunology
  • Tool sub type: Continuous
  • Parental cell: HT 1080
  • Organism: Human
  • Disease: Cancer
  • Description: The 2C4 cell line is a clonal derivative of the human fibrosarcoma cell line HT 1080. The 2C4 cell line clone expresses the simple cell-surface marker CD2 (normally expressed only on T cells) under the control of the 9-27 gene promoter. The 9-27 gene promoter is inducible by interferon gamma.
  • Biosafety level: 1
  • Cellosaurus id: CVCL_1D50

Handling

  • Format: Frozen
  • Growth medium: DMEM + 10% heat-inactivated FBS + 400ug G418 per ml (As described by Kohlhuber et al., 1997)
  • Unit size: 1x10^6 cells / vial
  • Shipping conditions: Dry ice
  • Storage conditions: Liquid Nitrogen
  • Mycoplasma free: Yes

Related Tools

  • Related tools: Gamma2A Jak2 Cell Line ; 2C4-Gamma2A cell line

References

  • Kohlhuber et al. 1997. Mol Cell Biol. 17(2):695-706. PMID: 9001223.
  • A JAK1/JAK2 chimera can sustain alpha and gamma interferon responses.
  • Watling et al. 1993. Nature. 366(6451):166-70. PMID: 7901766.
  • Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway.