Cat. #154232
HtrA3 (Clone 6G6)
Cat. #: 154232
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Long isoform Human HtrA3 (high temperature requirement factor A)
Class: Monoclonal
Application: IHC ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Hudson Institute Of Medical Research
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: HtrA3 (Clone 6G6)
- Alternate name: HtrA3, High-temperature requirement factor A3,Pregnancy-related serine protease
- Research fields: Tissue-specific biology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 48 kDa (46.9 kDa plus 1 kDa for the His tag)
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: IHC ; WB
- Description: Potential marker for preeclampsia. Detection of endogenous HtrA3 proteins in human serum HtrA3 are oligomeric serine proteases involved in protein quality control , regulate signal transduction in cell growth, apoptosis, inflammation in cancer, arthritis, neurodegenerative and neuromuscuclar disorders, age-related macular degeneration, pregnancy-specific disease preecampsia
- Immunogen: HtrA3-L-S305A protein
- Immunogen uniprot id: P83110, HTRA3_HUMAN
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Long isoform Human HtrA3 (high temperature requirement factor A)
- Molecular weight: 48 kDa (46.9 kDa plus 1 kDa for the His tag)
- Target background: Potential marker for preeclampsia. Detection of endogenous HtrA3 proteins in human serum HtrA3 are oligomeric serine proteases involved in protein quality control , regulate signal transduction in cell growth, apoptosis, inflammation in cancer, arthritis, neurodegenerative and neuromuscuclar disorders, age-related macular degeneration, pregnancy-specific disease preecampsia
Applications
- Application: IHC ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Dry ice
Related Tools
- Related tools: HtrA3 Monoclonal Antibody (Clone 3E6) ; HtrA3 Monoclonal Antibody (Clone 2C4) ; HtrA3 Monoclonal Antibody (Clone 9C9) ; HtrA3 Monoclonal Antibody (Clone 10H10)
References
- Wang et al. 2018. SLAS Discov. 23(10):1092-1099. PMID: 27932697.
- HtrA3 Isoform-Specific ELISAs for Early Detection of Preeclampsia.
- Activity-modulating monoclonal antibodies to the human serine protease HtrA3 provide novel insights into regulating HtrA proteolytic activities.
- Singh et al. 2014. PLoS One. 9(9):e108235. PMID: 25248123.
- HtrA3 as an early marker for preeclampsia: specific monoclonal antibodies and sensitive high-throughput assays for serum screening.
- Dynon et al. 2012. PLoS One. 7(9):e45956. PMID: 23049902.
