#152606

Anti-TNFRSF18 (soluble form) [T10P2H9*B9]

Cat. #152606

Anti-TNFRSF18 (soluble form) [T10P2H9*B9]

Cat. #: 152606

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18-soluble form), GITR

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling
Related Tools

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-TNFRSF18 (soluble form) [T10P2H9*B9]
  • Alternate name: Tumor Necrosis Factor Receptor Superfamily Member 18; Glucocorticoid-Induced TNFR-Related Protein; Activation-Inducible TNFR Family Receptor; AITR; GITR; TNF Receptor Superfamily Activation-Inducible Protein; CD357 Antigen; GITR-D; CD357
  • Research fields: Cancer;Cell signaling and signal transduction;Immunology
  • Clone: T10P2H9*B9
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 26 kDa
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: TNFRSF18 is a type I transmembrane protein with homology to members of divergent costimulatory molecules in the TNFRSF. To date three isoforms of TNFRSF18 have been identified, including one soluble form that lacks a transmembrane domain. According to homology of the cytoplasmic domain, TNFRSF18 and other three TNFRSF members (4–1BB, CD27, and OX40) probably constitute a new subfamily as divergent costimulators. TNFRSF18 and the other subfamily members bind TRAF molecules and activate NF-KB.
  • Immunogen: Ovalbumin conjugated peptide - PWQQKWVQE
  • Isotype: IgG1 kappa
  • Recommended controls: IHC- formalin-fixed, paraffin-embedded breast cancer sections; WB - Jurkat cell lysates

Target Details

  • Target: Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18-soluble form), GITR
  • Molecular weight: 26 kDa
  • Tissue cell line specificity: IHC- formalin-fixed, paraffin-embedded breast cancer sections; WB - Jurkat cell lysates
  • Target background: TNFRSF18 is a type I transmembrane protein with homology to members of divergent costimulatory molecules in the TNFRSF. To date three isoforms of TNFRSF18 have been identified, including one soluble form that lacks a transmembrane domain. According to homology of the cytoplasmic domain, TNFRSF18 and other three TNFRSF members (41BB, CD27, and OX40) probably constitute a new subfamily as divergent costimulators. TNFRSF18 and the other subfamily members bind TRAF molecules and activate NF-KB.

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

Related Tools

  • Related tools: Anti-TNFRSF18(r) [T9P4G4*D7] ; Anti-TNFRSF18 (soluble form), Recombinant [T10P2H9*B9]