#151160

Anti-Thrombospondin receptor [SMT]

Please Enter Your Email ID
Email ID

Cat. #151160

Anti-Thrombospondin receptor [SMT]

Cat. #: 151160

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Thrombospondin receptor (CD36)

Class: Monoclonal

Application: FACS ; IHC ; IP ; Fn ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Nancy Hogg

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Thrombospondin receptor [SMT]
  • Alternate name: SMO
  • Research fields: Cell biology;Cancer;Tissue-specific biology;Cell signaling and signal transduction;Metabolism;Neurobiology;Stem cell biology
  • Clone: SMT
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IP ; Fn ; WB
  • Description: CD36 is a class B scavenger receptor found in vascular endothelium, platelets and monocytes. CD36 binds thrombospondin and oxidised low density lipoprotein (LDL).
  • Immunogen: Tonsil cells and PBM
  • Isotype: IgM
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: Thrombospondin receptor (CD36)
  • Target background: CD36 is a class B scavenger receptor found in vascular endothelium, platelets and monocytes. CD36 binds thrombospondin and oxidised low density lipoprotein (LDL).

Applications

  • Application: FACS ; IHC ; IP ; Fn ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Pilling et al. 2009. PLoS One. 4(10):e7475. PMID: 19834619.
  • Identification of markers that distinguish monocyte-derived fibrocytes from monocytes, macrophages, and fibroblasts.
  • Biswas et al. 2007. PLoS Pathog. 3(9):1271-80. PMID: 17907801.
  • Plasmodium falciparum uses gC1qR/HABP1/p32 as a receptor to bind to vascular endothelium and for platelet-mediated clumping.
  • Pain et al. 2001. Proc Natl Acad Sci U S A. 98(4):1805-10. PMID: 11172032.
  • Platelet-mediated clumping of Plasmodium falciparum-infected erythrocytes is a common adhesive phenotype and is associated with severe malaria.
  • Wintergerst et al. 2000. Eur J Biochem. 267(19):6050-9. PMID: 10998066.
  • Apoptosis induced by oxidized low density lipoprotein in human monocyte-derived macrophages involves CD36 and activation of caspase-3.
  • Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.
  • Monoclonal antibodies specific for human monocytes, granulocytes and endothelium.