Cat. #151568
Anti-TFF1 [PS2GE1]
Cat. #: 151568
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Trefoil factor 1 (TFF1) also known as pS2/pNR2 Estrogen-regulated protein Ab2
Class: Monoclonal
Application: IHC ; IP
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-TFF1 [PS2GE1]
- Research fields: Cancer;Cell biology;Genetics
- Clone: PS2GE1
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 6.5 kDa
- Reactivity: Human
- Host: Mouse
- Application: IHC ; IP
- Description: pS2 is a cysteine-rich, 6.5kDa protein found in both oestrogen-dependent (breast tumours) and oestrogen-independent tissues (normal stomach mucosa). About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localisation to the Golgi apparatus. pS2 is primarily expressed in oestrogen receptor-positive breast tumours.
- Immunogen: A synthetic 31-mer peptide from the C-terminus of human pS2 protein
- Isotype: IgG1
- Recommended controls: Normal stomach or breast carcinoma
Target Details
- Target: Trefoil factor 1 (TFF1) also known as pS2/pNR2 Estrogen-regulated protein Ab2
- Molecular weight: 6.5 kDa
- Tissue cell line specificity: Normal stomach or breast carcinoma
- Target background: pS2 is a cysteine-rich, 6.5kDa protein found in both oestrogen-dependent (breast tumours) and oestrogen-independent tissues (normal stomach mucosa). About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localisation to the Golgi apparatus. pS2 is primarily expressed in oestrogen receptor-positive breast tumours.
Applications
- Application: IHC ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Williams et al. 1996. Hum Pathol. 27(12):1259-66. PMID: 8958295.
- Characterization of monoclonal antibodies raised to C-terminal peptides of pS2: a major trefoil peptide and motility factor expressed in adenocarcinomas and regions of mucosal injury.
