Cat. #153990
Anti-Omentin [3G1B3]
Cat. #: 153990
Unit size: 100 ug
Availability: 10-12 weeks
Target: Omentin
Class: Monoclonal
Application: IP ; WB
Reactivity: Human ; Mouse ; Rat
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: University of Maryland
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Omentin [3G1B3]
- Alternate name: Intelectin-1, ITLN1, hIntL-1
- Research fields: Immunology;Metabolism;Microbiology;Tissue-specific biology
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 120 kDa (trimer), 37 kDa (monomer)
- Reactivity: Human ; Mouse ; Rat
- Host: Mouse
- Application: IP ; WB
- Description: Monoclonal antibody which detects omentin, linked to diabetes. Background and Research Application: Omentin (human intelectin-1) is a secreted glycoprotein involved in the innate immune system as well as enhancing insulin-stimulated glucose uptake. Highly expressed in small intestine and adipose tissue and present at lower levels in testis, heart, pancreas, colon and skeletal muscle, intelectin-1 exists as a disulphide-linked homotrimer that functions to enhance insulin-stimulated glucose uptake and is also thought to participate in host defence against microorganisms. Serum levels of omentin are negatively correlated with obesity, suggesting a role in diabetes. More recently, omentin has been shown to interact with glycans on pathogenic bacteria.
- Immunogen: Q8WWA0
- Immunogen uniprot id: Q8WWA0
- Isotype: IgG
Target Details
- Target: Omentin
- Molecular weight: 120 kDa (trimer), 37 kDa (monomer)
- Target background: Monoclonal antibody which detects omentin, linked to diabetes. Background and Research Application Omentin (human intelectin-1) is a secreted glycoprotein involved in the innate immune system as well as enhancing insulin-stimulated glucose uptake. Highly expressed in small intestine and adipose tissue and present at lower levels in testis, heart, pancreas, colon and skeletal muscle, intelectin-1 exists as a disulphide-linked homotrimer that functions to enhance insulin-stimulated glucose uptake and is also thought to participate in host defence against microorganisms. Serum levels of omentin are negatively correlated with obesity, suggesting a role in diabetes. More recently, omentin has been shown to interact with glycans on pathogenic bacteria.
Applications
- Application: IP ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Dry ice
References
- Yang et al. 2006. Am J Physiol Endocrinol Metab. 290(6):E1253-61. PMID: 16531507.
- Identification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin action.
