Cat. #153899
Anti-O-linked N-acetylglucosamine (O-GlcNAc) [5F6.G4]
Cat. #: 153899
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: O-linked N-acetylglucosamine
Class: Monoclonal
Application: ELISA ; WB
Reactivity: Mammals
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Lance Wells
Institute: University of Georgia
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-O-linked N-acetylglucosamine (O-GlcNAc) [5F6.G4]
- Alternate name: O-GlcNAc
- Research fields: Cancer;Cell signaling and signal transduction;Genetics;Metabolism;Neurobiology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Mammals
- Host: Mouse
- Application: ELISA ; WB
- Description: The study of O-GlcNAc, a ubiquitous translation and transcription regulator which is found in a wide variety of proteins, is of great relevance to multiple chronic human and veterinary diseases. These include diabetes (and its effects in the heart, kidneys and eyes), cardiovascular disease, neurodegenerative disorders involving both plaque and tangle formation, inflammatory processes, liver disease, fibrosis, metabolic disorders and cancer. There is fast growing collection of evidence that O-GlcNAcylation plays a pivotal role in epigenetics.
- Immunogen: Synthetic peptide O-GlcNAc
- Isotype: IgG3
Target Details
- Target: O-linked N-acetylglucosamine
- Target background: The study of O-GlcNAc, a ubiquitous translation and transcription regulator which is found in a wide variety of proteins, is of great relevance to multiple chronic human and veterinary diseases. These include diabetes (and its effects in the heart, kidneys and eyes), cardiovascular disease, neurodegenerative disorders involving both plaque and tangle formation, inflammatory processes, liver disease, fibrosis, metabolic disorders and cancer. There is fast growing collection of evidence that O-GlcNAcylation plays a pivotal role in epigenetics.
Applications
- Application: ELISA ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
References
- Rios et al. 2016. Angew Chem Int Ed Engl. 55(10):3387-92. PMID: 26822115.
- Synthetic Receptors for the High-Affinity Recognition of O-GlcNAc Derivatives.
- Teo et al. 2010. Nat Chem Biol. 6(5):338-43. PMID: 20305658.
- Glycopeptide-specific monoclonal antibodies suggest new roles for O-GlcNAc.
