Cat. #156520
Anti-Myeloperoxidase (MPO) scFv (B10B) [B10BscFv]
Cat. #: 156520
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Myeloperoxidase
Class: Recombinant
Application: ELISA ; WB
Host: Chicken
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Barry McDonnell ; Caroline Murphy
Institute: Dublin City University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Myeloperoxidase (MPO) scFv (B10B) [B10BscFv]
- Alternate name: MPO
- Research fields: Tissue-specific biology
- Tool sub type: Primary antibody
- Class: Recombinant
- Purpose: Marker
- Conjugation: Unconjugated
- Host: Chicken
- Application: ELISA ; WB
- Description: MPO is a mediator enzyme secreted by inflammatory cells e.g. activated neutrophils and monocytes. MPO produces hypochlorous acid (HOCl) from hydrogen peroxide (H2O2) and chloride anion (Cl-) (or the equivalent from a non-chlorine halide) during the neutrophil's respiratory burst, requiring heme as a cofactor. Furthermore, it oxidizes tyrosine to tyrosyl radical using hydrogen peroxide as an oxidizing agent (Heinecke et al., 1993). Both hypochlorous acid and tyrosyl radical are cytotoxic and a...
- Immunogen: Myeloperoxidase
- Immunogen uniprot id: TBC
Target Details
- Target: Myeloperoxidase
- Target background: MPO is a mediator enzyme secreted by inflammatory cells e.g. activated neutrophils and monocytes. MPO produces hypochlorous acid (HOCl) from hydrogen peroxide (H2O2) and chloride anion (Cl-) (or the equivalent from a non-chlorine halide) during the neutrophil's respiratory burst, requiring heme as a cofactor. Furthermore, it oxidizes tyrosine to tyrosyl radical using hydrogen peroxide as an oxidizing agent (Heinecke et al., 1993). Both hypochlorous acid and tyrosyl radical are cytotoxic and a...
Applications
- Application: ELISA ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Storage buffer: 1 x PBS
- Storage conditions: -20° C avoid repeated freeze and thaw cycles
- Shipping conditions: Dry ice
References
- McDonnell, Barry (2010) Development of novel antibody-based diagnostics for the early and rapid detection of cardiac markers. PhD thesis, Dublin City University.
