#152644

Anti-MOAP-1 [4A12]

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Cat. #152644

Anti-MOAP-1 [4A12]

Cat. #: 152644

Sub-type: Primary antibody

Unit size: 100 ug

Target: Modulator of apoptosis-1

Class: Monoclonal

Application: IF ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: A*STAR Accelerate Technologies Pte Ltd

Tool Details
Target Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-MOAP-1 [4A12]
  • Research fields: Apoptosis and autophagy;Cancer
  • Clone: 4A12
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IF ; WB
  • Description: MOAP-1, also known as MAP-1 (Modulator of apoptosis-1) was initially identified as a Bax-associating protein from a yeast two-hybrid screen using Bax as bait. MOAP-1 is enriched in mitochondria and appears to be an effector for mediating Bax function in mitochondria. Moreover, in supporting the idea that MOAP-1 may be involved in a tumor suppressor axis, MOAP-1 is found to associate with the tumor suppressor RASSF1A to mediate Bax-dependent apoptosis in response to death receptor activation in tumor cells.
  • Immunogen: GST-MOAP-1 (N-terminal) fusion protein
  • Isotype: IgG1
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: Modulator of apoptosis-1
  • Target background: MOAP-1, also known as MAP-1 (Modulator of apoptosis-1) was initially identified as a Bax-associating protein from a yeast two-hybrid screen using Bax as bait. MOAP-1 is enriched in mitochondria and appears to be an effector for mediating Bax function in mitochondria. Moreover, in supporting the idea that MOAP-1 may be involved in a tumor suppressor axis, MOAP-1 is found to associate with the tumor suppressor RASSF1A to mediate Bax-dependent apoptosis in response to death receptor activation in tumor cells.

Applications

  • Application: IF ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C