#151127

Anti-Keratin7 [LP5K]

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Cat. #151127

Anti-Keratin7 [LP5K]

Cat. #: 151127

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Keratin 7

Class: Monoclonal

Application: FACS ; IHC ; IF ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Birgit Lane

Institute: Queen Mary University of London

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Keratin7 [LP5K]
  • Research fields: Cell signaling and signal transduction
  • Clone: LP5K
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Molecular weight: 54 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IF ; WB
  • Description: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair roo...
  • Immunogen: Sonicated cytoskeleton fractions (insoluble in 1% Nonidet-P40) from SV40 transformed neonatal keratinocytes.
  • Isotype: IgG2b
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: Keratin 7
  • Molecular weight: 54 kDa
  • Tissue cell line specificity: Mouse
  • Target background: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair roo...

Applications

  • Application: FACS ; IHC ; IF ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Lane EB et al. 1985. Ann. NY Acad. Sci. 455:241-58.PMID: 2417515
  • Sato et al. 2005. Blood. 106(2):428-35. PMID: 15797992.
  • Platelet-derived soluble factors induce human extravillous trophoblast migration and differentiation: platelets are a possible regulator of trophoblast infiltration into maternal spiral arteries.
  • Sato et al. 2003. Development. 130(22):5519-32. PMID: 14530297.
  • Trophoblasts acquire a chemokine receptor, CCR1, as they differentiate towards invasive phenotype.
  • Markey ...