Cat. #160673
Anti-human blood group B antigen [O10]
Cat. #: 160673
Unit size: 100 ug
Availability: 10-12 weeks
Target: Human blood group B antigen
Class: Monoclonal
Application: Fn ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Tomasz Klaus ; Monika Bzowska ; Joanna Bereta
Institute: Jagiellonian University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-human blood group B antigen [O10]
- Research fields: Genetics
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: Fn ; WB
- Description: From Klaus et al. Sci Rep. 2016 Aug 3;6:30938. Mouse immunoglobulins M (IgMs) that recognize human blood group antigens induce haemagglutination and are used worldwide for diagnostic blood typing. Contrary to the current belief that IgGs are too small to simultaneously bind antigens on two different erythrocytes, we obtained agglutinating mouse IgG3 that recognized antigen B of the human ABO blood group system.
- Immunogen: Human red blood cells
- Isotype: IgM
- Myeloma used: Sp2/0
Target Details
- Target: Human blood group B antigen
- Target background: From Klaus et al. Sci Rep. 2016 Aug 3;6:30938. Mouse immunoglobulins M (IgMs) that recognize human blood group antigens induce haemagglutination and are used worldwide for diagnostic blood typing. Contrary to the current belief that IgGs are too small to simultaneously bind antigens on two different erythrocytes, we obtained agglutinating mouse IgG3 that recognized antigen B of the human ABO blood group system.
Applications
- Application: Fn ; WB
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Dry ice
References
- Klaus et al. 2018. Sci Rep. 8(1):519. PMID: 29323348.
- Klaus et al. 2016. Sci Rep. 6:30938. PMID: 27484487.
