Cat. #156385
Anti-CUL-4A
Cat. #: 156385
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Cullin 4A
Class: Polyclonal
Application: WB ; IP ; ChIP ; ELISA ; IHC
Reactivity: Human ; Mouse
Host: Rabbit
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: University of Illinois Chicago
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CUL-4A
- Alternate name: CUL-4A
- Research fields: Biochemistry;Cancer;Cell biology;Genetics
- Tool sub type: Primary antibody
- Class: Polyclonal
- Conjugation: Unconjugated
- Reactivity: Human ; Mouse
- Host: Rabbit
- Application: WB ; IP ; ChIP ; ELISA ; IHC
- Description: CUL-4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle. Moreover, CUL-4A is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins. As a result, CUL-4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV.
- Immunogen: Synthetic peptide (ERDKDNPNQYHYVA) (746-759, C-terminus peptide), corresponding to human CUL-4A was conjugated to maleimide-activated keyhole limpet hemocyanin
Target Details
- Target: Cullin 4A
- Target background: CUL-4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle. Moreover, CUL-4A is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins. As a result, CUL-4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV.
Applications
- Application: WB ; IP ; ChIP ; ELISA ; IHC
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Dry ice
References
- Sharma et al. 2014. Open Biol. 4:130217. PMID: 24522884.
- Shiyanov et al. 1999. J Biol Chem. 274(50):35309-12. PMID: 10585395.
