Cat. #153326
Anti-CEACAM3/5 (CD66d/e) [308/3-3]
Cat. #: 153326
Unit size: 100 ug
Availability: 3-4 weeks
Target: CEACAM3/5, CD66d, CD66e
Class: Monoclonal
Application: ELISA ; FACS ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Bernhard B. Singer
Institute: LeukoCom
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CEACAM3/5 (CD66d/e) [308/3-3]
- Alternate name: CD66d, CD66e
- Research fields: Immunology
- Clone: 308/3-3
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 30, 180
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; FACS ; IP ; WB
- Description: Monoclonal antibody directed against a shared epitope between CEACAM3 and 5. Background and Research Application Carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 3/5 belong to the immunoglobulin superfamily. These proteins contain 1 Ig-like V-type (immunoglobulin-like) domain and the cytosolic domain is involved in S100A9 interaction. CEACAMs are reported to participate in diverse physiological processes, including cell adhesion, differentiation, proliferation, and survival, as well as in carcinogenesis and bacterial pathogenesis. CEACAM molecules play a crucial role within the innate immune system, via phagocytosis and pathogen clearance. This antibody reacts with an antigen epitope shared by CEACAM 3 and 5.
- Immunogen: Recombinant soluble human CEACAM3-Fc produced in HEK293 cells
- Immunogen uniprot id: P40198
- Isotype: IgG1 kappa
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: CEACAM3/5, CD66d, CD66e
- Molecular weight: 30, 180
- Target background: Monoclonal antibody directed against a shared epitope between CEACAM3 and 5. Background and Research Application Carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 3/5 belong to the immunoglobulin superfamily. These proteins contain 1 Ig-like V-type (immunoglobulin-like) domain and the cytosolic domain is involved in S100A9 interaction. CEACAMs are reported to participate in diverse physiological processes, including cell adhesion, differentiation, proliferation, and survival, as well as in carcinogenesis and bacterial pathogenesis. CEACAM molecules play a crucial role within the innate immune system, via phagocytosis and pathogen clearance. This antibody reacts with an antigen epitope shared by CEACAM 3 and 5.
Applications
- Application: ELISA ; FACS ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
