Cat. #153581
Anti-CD11a [BU17]
Cat. #: 153581
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: CD11a
Class: Monoclonal
Application: FACS
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Margaret Goodall
Institute: University of Birmingham
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-CD11a [BU17]
- Alternate name: Integrin alpha L; lymphocyte function-associated antigen 1 alpha polypeptide; ITGAL; cell differentiation 11a
- Research fields: Cell signaling and signal transduction
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: FACS
- Description: CD11A encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of alpha and beta chains. This L-domain containing alpha integrin combines with the beta 2 chain to form the integrin lymphocyte function-associated antigen-1 expressed on all leukocytes and this plays a central role in leukocyte intercellular adhesion through interactions with its ligands.
- Immunogen: Waldenstroms macroglobulinaemia a late B cell line with surface and secreted IgM Kappa
- Isotype: IgG1
Target Details
- Target: CD11a
- Target background: CD11A encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of alpha and beta chains. This L-domain containing alpha integrin combines with the beta 2 chain to form the integrin lymphocyte function-associated antigen-1 expressed on all leukocytes and this plays a central role in leukocyte intercellular adhesion through interactions with its ligands.
Applications
- Application: FACS
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Rezzonico et al. 2001. Blood. 97(10):2932-40. PMID: 11342414.
- Ligation of CD11b and CD11c beta(2) integrins by antibodies or soluble CD23 induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta production in primary human monocytes through a pathway dependent on nuclear factor-kappaB.
- Baker et al. 1998. Blood. 92(8):2830-43. PMID: 9763568.
- Prolonged phenotypic, Fn, and molecular change in group I Burkitt lymphoma cells on short-term exposure to CD40 ligand.
