#158326

NBQ-38 small molecule

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Cat. #158326

NBQ-38 small molecule

Cat. #: 158326

Sub-type: Inhibitor

Availability: Please enquire for quantities and pricing

Application: cell hypoxia marker

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Osvaldo Cox (Retired), Beatriz Zayas

Institute: Universidad Ana G. Mendez

Tool Details
Handling
Target Details
Application Details
References

Tool Details

*FOR RESEARCH USE ONLY

  • Tool name: NBQ-38 small molecule
  • Research fields: Cancer;Cell biology
  • Molecular formula: C17H14ClN3O2
  • Tool sub type: Inhibitor
  • Description: Inhibitor of growth in several cancer cell line models. This small molecule can also be used as a cell hypoxia marker.
  • Application: cell hypoxia marker
  • Iupac: 7-Ethyl-3-nitrobenzimidazolo[3,2-a]quinolinium Chloride
  • Molecular weight: 327.77
  • Solubility: 100 ľg/mL in DMSO

Handling

  • Purity: 327.77 g/mol
  • Shipping conditions: Dry Ice

Target Details

  • Ic50: 36-38 uM (A431 cells); 950 uM+/- 26 uM (U937 cells)

Application Details

  • Application: cell hypoxia marker

References

  • VĂŠlez et al. 2013. Open J Apoptosis. 2(2):13-22. PMID: 25243104.
  • Zayas et al. 2007. Toxicol In Vitro. 21(6):1155-64. PMID: 17466486.
  • Vivas-MejĂ­a et al. 1998. Mol Cell Biochem. 178(1-2):203-12. PMID: 9546601.