Cat. #158381
Transient receptor potential ankyrin 1 (TRPA1)-GFP HeLa cell line
Cat. #: 158381
Unit size: 1x10^6 cells / vial
Availability: 10-12 weeks
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Peter Bradding ; Harvinder Virk
Institute: University of Leicester
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Transient receptor potential ankyrin 1 (TRPA1)-GFP HeLa cell line
- Research fields: Neurobiology
- Parental cell: HeLa
- Conditional: No
- Description: The transient receptor potential cation channel family member ankyrin 1 (TRPA1) is an ion channel with high Ca2+ permeability that is activated by numerous noxious stimuli and by multiple products of oxidative stress. TRPA1 is a drug target with antagonists in phase I and II clinical trials. It is considered a potential target in multiple pain conditions including neuropathic, inflammatory and migraine pain, in addition to cough sensitivity, airway inflammation and fibrosisThis HeLa cell line is stably transfected with a dual-gene promotor (pCDH-CMV-MCS-EF1-copGFP) to express both GFP and hTRPA1.Forward TRPA1 Xba1 gggtctagaATGAAGCGCAGCCTGAGGAAG Reverse TRPA1 NotI ggggcggccgcttaAGGCTCAAGATGGTGTGTTTTTGCC
Target Details
- Target: human Transient receptor potential cation channel family member ankyrin 1 (hTRPA1)
Handling
- Format: Frozen
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
Related Tools
- Related tools: Transient receptor potential cation channel superfamily M member 2 (TRPM2)-GFP HeLa cell line ; HeLa pCDH-CMV-MCS-EF1-copGFP Control Cell Line