Cat. #153755
THCECb Cell Line
Cat. #: 153755
Unit size: 1x10^6 cells / vial
Availability: 3-4 weeks
Organism: Human
Tissue: Cervix
Disease: Neisseria gonorrhoeae infection
Model: Immortalised Line
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Michael Apicella
Institute: The University of Iowa
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: THCECb Cell Line
- Research fields: Immunology
- Organism: Human
- Tissue: Cervix
- Disease: Neisseria gonorrhoeae infection
- Model: Immortalised Line
- Conditional: No
- Description: This cell line was developed to study Neisseria gonorrhoeae (Gonorrhea) infection in women. Women with N. gonorrhoeae are often asymptomatic leading to chronic infections, upper genital tract infections leading to pelvic inflammatory disease, and increase risk for contracting HIV. This cell line has been used in studying biofilm production of N. gonorrhoeae which can exacerbate the illness and infection.This cell line expresses complement receptor type III on the surface and secretes complement components, necessary for gonococcal attachment and invasion of cervical epithelial cells.
- Production details: This cell line was derived from primary cervical cells obtained from cervical biopsies and immortalized with E6/E7.
Target Details
- Target: Sexually transmitted diseases (STIs)
Handling
- Format: Frozen
- Growth medium: Serum-free keratinocyte growth media (K-SFM) supplement 500 mL of basal media with 12.5 mg BPE and 0.08 ug EGF. Media may be supplemented with 15 PenStrep for routine maintenance.
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
