Family 3 sibling – LAD-III EBV Lymphoblastoid Cell Line

An EBV-transformed B lymphoblastoid cell line (LCL) derived from the sibling of a Turkish subject that has Leukocyte Adhesion Deficiency-III (LAD-III) with a mutation in the kindlin-3 gene. LCLs are…

Contributors

Inventor Institute
Nancy Hogg Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Cat. #: 153771
Unit size: 1×10^6 cells / vial
Cancer types: Blood cancer
Research Fields: Cell biology;Immunology
Organism: Human
Tissue: Blood
Growth properties: Suspension, lymphoblastoid cell line
Cancer Types In Detail: Leukocyte Adhesion Deficiency-III (LAD-III)
Alternate name: Fermitin family homolog 3, MIG2-like protein, Unc-112-related protein 2
Product description: An EBV-transformed B lymphoblastoid cell line (LCL) derived from the sibling of a Turkish subject that has Leukocyte Adhesion Deficiency-III (LAD-III) with a mutation in the kindlin-3 gene. LCLs are also available from the subject, mother and father. This cell line was derived from 'Family 3 sibling' as described in Svensson et al. 2009. N.Nat Med. 2009 Mar;15(3):306-12. PMID: 19234463
disease: Cancer
Format: Frozen
Storage conditions: Liquid Nitrogen
Shipping conditions: Dry ice
Growth medium: RPMI-1640 + 10% FCS
Mycoplasma free: Yes
Biosafety level: 1
References:

Svensson et al. 2009. Nat Med. 15(3):306-12. PMID: 19234463.

Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation.

Related Tools for Cell lines

Cat. # Tool Name
151446 FLYRD18 Cell Line Key Info View Tool
151448 CMT 167 Cell Line Key Info View Tool
151484 2fTGH Cell Line Key Info View Tool
151629 MEF Raf1 FF/FF KI Cell Line Key Info View Tool
151631 C-Raf KI D486A Cell Line Key Info View Tool

Related News

UM-UC-10 Cell Line. Image courtesy of the European Collection of Authenticated Cell Cultures (ECACC), UK.
Cell Lines

Popular cell lines now available only from CancerTools.org

Read More
Cell Lines

New cell lines: murine melanocyte and melanoblast cell lines from Dr. Elena Sviderskaya

Read More
Image Reference: 2x PTEN -/- mouse prostate cancer cell lines (MuCap system). Histology staining of syngraft tumours (Van Duijn et al., 2018).
Cell Lines

38 new prostate cancer cell lines

Read More

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.