Cat. #157660
DLKP-M cell line
Cat. #: 157660
Sub-type: Continuous
Unit size: 1x10^6 cells / vial
Availability: 8-10 weeks
Organism: Human
Tissue: Lung
Disease: Cancer
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Martin Clynes
Institute: Dublin City University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: DLKP-M cell line
- Cancer: Lung cancer
- Cancers detailed: Lung carcinoma
- Research fields: Cancer
- Tool sub type: Continuous
- Parental cell: DLKP
- Organism: Human
- Tissue: Lung
- Disease: Cancer
- Growth properties: Monolayer
- Description: Mesenchymal-like sub-population cloned at NCTCC from DLKP P5, about 5% of DLKP cells show DLKP-M morphology, interconversion with -I, closest to normal chromosome number, fold resistance comp. to DLKP: 0.8 Adr; 0.95 Vcr; 0.7 VP-16. Immunocytochemistry: cytokeratin (all)-; GFAP-vimentin+; neurofilament+; P-gp-; a2- integrin++; 703D4+; 704A1 +; desmin-. More invasive in vitro than DLKP-SQ.
- Production details: Single cell cloning from DLKP parental population
- Biosafety level: 1
- Recommended controls: DLKP parental line
- Cellosaurus id: CVCL_H739
Target Details
- Target: DLKP
Handling
- Format: Frozen
- Growth medium: DMEM/Ham's F12, 5% FCS. Split 1:5, medium change 2-3 times weekly. Freezing method: 10% DMSO in FBS
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
- Storage conditions: Liquid Nitrogen
- Mycoplasma free: Yes
References
- O'Sullivan et al. 2014. Tumour Biol. 35(7):6983-97. PMID: 24744142.
- Keenan et al. 2012. Exp Cell Res. 318(5):593-602. PMID: 22281030.
- McBride et al. 1998. Tumour Biol. 19(2):88-103. PMID: 9486560.
