Cat. #151675
PEO14 Cell Line
Cat. #: 151675
Unit size: 1x10^6 cells / vial
Organism: Human
Tissue: Ovary
Disease: Cancer
Model: Tumour line
£575.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Simon Langdon
Institute: Cancer Research UK Edinburgh Centre
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: PEO14 Cell Line
- Cancer: Adenocarcinoma
- Cancers detailed: Adenocarcinoma
- Research fields: Cancer;Drug development
- Organism: Human
- Tissue: Ovary
- Disease: Cancer
- Growth properties: Adherent
- Model: Tumour line
- Conditional: Yes
- Description: The PEO14 cell line is one of nine from the PE ovarian adenocarcinoma panel (derived from 4 patients at varying stages of ovarian cancer, isolated from various malignant sites, and at various treatment stages) which provides a model system for research into the mechanism of oestrogen action on ovarian adenocarcinoma tumour cells, and for the study of efficacy and toxicity of oestrogen protagonists. PEO14 is an adherent cell line derived from a malignant effusion from the peritoneal ascites of a patient with a well differentiated serous adenocarcinoma. PEO14 was collected prior to treatment. PEO14 exhibits poor growth in semi-solid medium (agar). PEO14 is from the same patient as PEO16
- Cellosaurus id: CVCL_2687
Handling
- Format: Frozen
- Growth medium: RPMI-1640 + 2mM Glutamine + 2mM Sodium Pyruvate + 10% Foetal Bovine Serum.
- Unit size: 1x10^6 cells / vial
- Shipping conditions: Dry ice
- Subculture routine: Split sub-confluent cultures (70-80%) 1:4 to 1:10 seeding at 2- 3 x 10^4 cells/cm² using 0.05% trypsin or trypsin/EDTA; 5% CO₂; 37°C. Doubling time approximately 108 hours.
Related Tools
- Related tools: PEO1 Cell Line ; PEO1 Cell Line ; PEO4 Cell Line ; PEO6 Cell Line ; PEO16 Cell Line ; PEO23 Cell Line ; PEO1-CDDP Cell Line ; PEA1 Cell Line ; PEA2 Cell Line ; TO14 Cell Line
References
- Langdon et al. 1990. Br J Cancer. 62(2):213-6. PMID: 2386737.
- Oestrogen receptor expression and the effects of oestrogen and tamoxifen on the growth of human ovarian carcinoma cell lines.
- Degos et al. 1979. Gastroenterol Clin Biol. 3(10):735-9. PMID: 316786.
- [The natural history of gastrointestinal bleeding in patients with alcoholic cirrhosis. Definition of a subgroup of patients with high risk of bleeding recurrence (author's transl)]
