This antibody can be used to detect expression of latent vFLIP in KSHV infected cells and tumours and for examining the role of vFLIP in cell signaling.
| Inventor | Institute |
|---|---|
| Mary Collins | University College London (UCL) |
| Cat. #: | 151778 |
|---|---|
| Unit size: | 100 ug |
| Research Fields: | Apoptosis and autophagy;Cell biology;Microbiology |
| Application: | WB ; IHC; IP ; WB |
| Target: | vFlip |
| Reactivity: | Human |
| Host: | Rat |
| Class: | Monoclonal |
| Product description: | v-FLIP synthesis can be up-regulated when apoptosis is triggered. It may provide a survival advantage for KSHV-infected cells under some circumstances and could be a reason for an IRES-dependent translation of v-FLIP. This antibody can be used to detect expression of latent vFLIP in KSHV infected cells and tumours and for examining the role of vFLIP in cell signaling. |
|---|---|
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Immunogen: | Full-length recombinant v-FLIP expressed in Escherichia coli |
| Target background: | v-FLIP synthesis can be up-regulated when apoptosis is triggered. It may provide a survival advantage for KSHV-infected cells under some circumstances and could be a reason for an IRES-dependent translation of v-FLIP. This antibody can be used to detect expression of latent vFLIP in KSHV infected cells and tumours and for examining the role of vFLIP in cell signaling. |
|---|
| Format: | Liquid |
|---|---|
| Concentration: | 1 mg/ml |
| Storage buffer: | PBS with 0.02% azide |
| Storage conditions: | -15° C to -25° C |
| Shipping conditions: | Dry ice |
| References: |
Low et al. 2001. J Virol. 75:2938-45 PMID: 11222719 Field et al. 2003. J Cell Sci. 116(Pt 18):3721-8. PMID: 12890756 |
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