Anti-UCP1 [Vab12 P4B12*A12]

UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.

Contributors

Inventor Institute
Ayham Alnabulsi Vertebrate Antibodies Limited
Cat. #: 152686
Tool sub type: Primary antibody
Unit size: 100 ug
Research Fields: Cancer;Cell signaling and signal transduction;Metabolism
Application: ELISA ; IHC ; WB
Target: Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1)
Reactivity: Human
Clone: Vab12 P4B12*A12
Host: Mouse
Class: Monoclonal
Product description: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
Conjugation: Unconjugated
Isotype: IgG1 kappa
Immunogen: Ovalbumin-conjugated synthetic peptide – (10 amino acids) derived from the middle polypeptide region of human UCP1. The exact sequence is proprietary.
Myeloma used: P3X63Ag8.653
Target background: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
Format: Liquid
Concentration: 1 mg/ml
Storage buffer: PBS with 0.02% azide
Storage conditions: -15° C to -25° C
Shipping conditions: Dry ice
References:

The expression of brown fat-associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis.

The expression of brown fat associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis. Alnabulsi et al. 2019. Int J Cancer.

Images

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Immunohistochemical staining of human breast cancer tissue shows cytoplasmic positivity. IHC was performed on formalin-fixed; paraffin-embedded tissue sections.

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