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#152686

Anti-UCP1 [Vab12 P4B12*A12]

Cat. #152686

Anti-UCP1 [Vab12 P4B12*A12]

Cat. #: 152686

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1)

Class: Monoclonal

Application: ELISA ; IHC ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-UCP1 [Vab12 P4B12*A12]
  • Research fields: Cancer;Cell signaling and signal transduction;Metabolism
  • Clone: Vab12 P4B12*A12
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IHC ; WB
  • Description: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.
  • Immunogen: Ovalbumin-conjugated synthetic peptide - (10 amino acids) derived from the middle polypeptide region of human UCP1. The exact sequence is proprietary.
  • Isotype: IgG1 kappa
  • Myeloma used: P3X63Ag8.653
  • Recommended controls: WB- Jurkat whole cell lysate or overexpression cell lysate; IHC-formalin-fixed, paraffin-embedded human breast cancer

Target Details

  • Target: Uncoupling Protein 1 (Mitochondrial, Proton Carrier) (UCP1)
  • Tissue cell line specificity: WB- Jurkat whole cell lysate or overexpression cell lysate; IHC-formalin-fixed, paraffin-embedded human breast cancer
  • Target background: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat.

Applications

  • Application: ELISA ; IHC ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Dry ice

References

  • The expression of brown fat-associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis.
  • The expression of brown fat associated proteins in colorectal cancer and the relationship of uncoupling protein 1 with prognosis. Alnabulsi et al. 2019. Int J Cancer.

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