Cat. #160704
Anti-TLT-1 [4.8]monoclonal antibody
Cat. #: 160704
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Triggering Receptors Expressed on Myeloid cells (TREM)- like transcript-1 (TLT-1)
Class: Monoclonal
Application: WB ; IP
Reactivity: Mouse
Host: Rabbit
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Anthony Valance Washington
Institute: University of Puerto Rico
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-TLT-1 [4.8]monoclonal antibody
- Research fields: Cell biology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Mouse
- Host: Rabbit
- Application: WB ; IP
- Description: Mouse anti-TLT-1 (clone 4.8) monoclonal antibody. These rabbit hybridoma cells produce a monoclonal antibody to The membrane receptor Triggering Receptors Expressed on Myeloid cells (TREM)- like transcript-1 (TLT-1), located on alpha-granules of platelets. TREM-like transcript-1 (TLT-1) is involved in thrombus formation and platelet aggregation, inflammatory modulation, immune responses. Members of the TREM family are key regulators of innate and adaptive immune responses. According to Manfredi, et al., 2018, murine TLT-1 share a 65% identity with human TLT-1 and have been used to support existing clinical data that enable a better understanding of thrombotic and inflammatory diseases.
- Immunogen: Rabbits were immunized with the negatively charged region of the mTLT-1 extracellular domain 122PPVPGPREGEEAEDEK139.
Target Details
- Target: Triggering Receptors Expressed on Myeloid cells (TREM)- like transcript-1 (TLT-1)
- Target background: These rabbit hybridoma cells produce a monoclonal antibody to The membrane receptor Triggering Receptors Expressed on Myeloid cells (TREM)- like transcript-1 (TLT-1), located on alpha-granules of platelets. TREM-like transcript-1 (TLT-1) is involved in thrombus formation and platelet aggregation, inflammatory modulation, immune responses. Members of the TREM family are key regulators of innate and adaptive immune responses. According to Manfredi, et al., 2018, murine TLT-1 share a 65% identit...
Applications
- Application: WB ; IP
Handling
- Format: Liquid
- Unit size: 100 ug
- Shipping conditions: Shipping at 4° C
References
- Manfredi et al. 2018. Monoclon Antib Immunodiagn Immunother. 37(2):78-86. PMID: 29708866.
