Cat. #151323
Anti-TCP1a [91a (CTA-191)]
Cat. #: 151323
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: T-complex polypeptide 1 alpha (TCP1a)
Class: Monoclonal
Application: IP ; WB
Reactivity: Human ; Mouse ; Rat ; Dog ; Rabbit ; Bovine ; Pig ; Saccharomyces
Host: Rat
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: The Institute of Cancer Research
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-TCP1a [91a (CTA-191)]
- Research fields: Apoptosis and autophagy;Cancer;Cell biology
- Clone: 91a (CTA-191)
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 80 kDa
- Reactivity: Human ; Mouse ; Rat ; Dog ; Rabbit ; Bovine ; Pig ; Saccharomyces
- Host: Rat
- Application: IP ; WB
- Description: TCP1, (a constituent of chaperone-containing TCP-1, CCT) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells and upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin.
- Immunogen: C-terminal half of the full length murine TCP protein
- Isotype: IgG2a
- Myeloma used: Y3.AG.1.2.3
- Recommended controls: Mouse spleen and LHK35.2 cells
Target Details
- Target: T-complex polypeptide 1 alpha (TCP1a)
- Molecular weight: 80 kDa
- Tissue cell line specificity: Mouse spleen and LHK35.2 cells
- Target background: TCP1, (a constituent of chaperone-containing TCP-1, CCT) is a ~60 kDa protein constitutively expressed in almost all eukaryotic cells and upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone that is known to be involved in the folding of actin and tubulin.
Applications
- Application: IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Sternlicht et al. 1993. Proc Natl Acad Sci U S A. 90(20):9422-6. PMID: 8105476.
- The t-complex polypeptide 1 complex is a chaperonin for tubulin and actin in vivo.
- Harrison-Lavoie et al. 1993. EMBO J. 12(7):2847-53. PMID: 8335000.
- A 102 kDa subunit of a Golgi-associated particle has homology to beta subunits of trimeric G proteins.
- Willison et al. 1989. Cell. 57(4):621-32. PMID: 2655925.
- The t complex polypeptide 1 (TCP-1) is associated with the cytoplasmic aspect of Golgi membranes.
