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#151875

Anti-POT1 [M1-P1H5]

Cat. #151875

Anti-POT1 [M1-P1H5]

Cat. #: 151875

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Protection of telomeres 1 (POT1)

Class: Monoclonal

Application: ELISA ; IF ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Ayham Alnabulsi

Institute: Vertebrate Antibodies Limited

Tool Details
Target Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-POT1 [M1-P1H5]
  • Research fields: Cancer;Cell biology;Genetics
  • Clone: M1-P1H5
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: ELISA ; IF ; WB
  • Description: POT1 (protection of telomeres 1) is part of the telomerase ribonucleotide (RNP) complex, which stabilises chromosomes by controlling telomere elongation. POT1 is a component of the double-stranded telomeric DNA-binding TRF1 complex which cis-inhibits telomerase. POT1 localization on telomeres diminishes in the absence of single-stranded DNA.
  • Immunogen: Peptide sequence - IPASEVLMDD
  • Isotype: IgG1 kappa
  • Recommended controls: ELISA- Peptide immunogenWestern Blot- Hela cell extract (nuclear fraction)IF- Hela Cells

Target Details

  • Target: Protection of telomeres 1 (POT1)
  • Tissue cell line specificity: ELISA- Peptide immunogenWestern Blot- Hela cell extract (nuclear fraction)IF- Hela Cells
  • Target background: POT1 (protection of telomeres 1) is part of the telomerase ribonucleotide (RNP) complex, which stabilises chromosomes by controlling telomere elongation. POT1 is a component of the double-stranded telomeric DNA-binding TRF1 complex which cis-inhibits telomerase. POT1 localization on telomeres diminishes in the absence of single-stranded DNA.

Applications

  • Application: ELISA ; IF ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Dry ice

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