#151787

Anti-PDGFR alpha [PDGFR-H7A]

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Cat. #151787

Anti-PDGFR alpha [PDGFR-H7A]

Cat. #: 151787

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-5 days

Target: PDGFR alpha, platelet-derived growth factor receptor, alpha polypeptide.

Class: Monoclonal

Application: IP

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Jacqueline Cordell

Institute: University of Oxford

Tool Details
Target Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-PDGFR alpha [PDGFR-H7A]
  • Research fields: Cell signaling and signal transduction;Developmental biology;Disease (not cancer)
  • Clone: PDGFR-H7A
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: IP
  • Description: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
  • Immunogen: Recombinant protein corresponding to amino acids 1 to 78 of human PDGFRA
  • Isotype: IgG1 lambda
  • Myeloma used: NS0
  • Recommended controls: Human Hela cell line

Target Details

  • Target: PDGFR alpha, platelet-derived growth factor receptor, alpha polypeptide.
  • Tissue cell line specificity: Human Hela cell line
  • Target background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the Fn receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Applications

  • Application: IP

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C