#151191

Anti-ORC1 [ORC1 7F6/1]

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Cat. #151191

Anti-ORC1 [ORC1 7F6/1]

Cat. #: 151191

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-5 days

Target: ORC1

Class: Monoclonal

Application: IP ; ChIP ; ELISA ; IHC ; IP ; WB ; ChIP-seq

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-ORC1 [ORC1 7F6/1]
  • Research fields: Genetics
  • Clone: ORC1 7F6/1
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 45-97 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: IP ; ChIP ; ELISA ; IHC ; IP ; WB ; ChIP-seq
  • Description: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
  • Immunogen: Bacterially expressed Human ORC1
  • Isotype: IgG1
  • Myeloma used: Sp2/0-Ag14

Target Details

  • Target: ORC1
  • Molecular weight: 45-97 kDa
  • Target background: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.

Applications

  • Application: IP ; ChIP ; ELISA ; IHC ; IP ; WB ; ChIP-seq

Handling

  • Format: Liquid
  • Concentration: 0.76 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Lu et al. 2016. Biol Open. 5(10):1449-1460. PMID: 27744293.
  • Beck et al. 2012. Genes Dev. 26(23):2580-9. PMID: 23152447.
  • Salsi et al. 2009. Mol Cell Biol. 29(21):5775-88. PMID: 19703996.
  • Burke et al. 2001. J Biol Chem. 276(18):15397-408. PMID: 11278932.