#153991

Anti-LRP1 [8G1]

Cat. #153991

Anti-LRP1 [8G1]

Cat. #: 153991

Sub-type: Primary antibody

Unit size: 100 ug

Target: Low density lipoprotein receptor-related protein-1, heavy chain

Class: Monoclonal

Application: IHC ; WB ; EM (EM) ; DB ; FACS

Reactivity: Mouse ; Rat ; Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: University of Maryland

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-LRP1 [8G1]
  • Alternate name: LRP1, Low density lipoprotein receptor-related protein 1, apolipoprotein E receptor (APOER), cluster of differentiation 91 (CD91), alpha-2-macroglobulin receptor (A2MR)
  • Research fields: Cell signaling and signal transduction;Genetics;Neurobiology
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Molecular weight: 85/515/700 kDA
  • Reactivity: Mouse ; Rat ; Human
  • Host: Mouse
  • Application: IHC ; WB ; EM (EM) ; DB ; FACS
  • Description: LRP1 is an endocytic receptor that interacts with several ligands including alpha 2-macroglobulin. Functionally, the receptor mediates cellular signalling with implications in Alzheimer's disease. This receptor is expressed in brain, liver, and lung and localized to the cytoplasm and nucleus.
  • Immunogen: full length LRP-1 protein
  • Isotype: IgG1

Target Details

  • Target: Low density lipoprotein receptor-related protein-1, heavy chain
  • Molecular weight: 85/515/700 kDA
  • Tissue cell line specificity: Mouse
  • Target background: LRP1 is an endocytic receptor that interacts with several ligands including alpha 2-macroglobulin. Fnly, the receptor mediates cellular signalling with implications in Alzheimer's disease. This receptor is expressed in brain, liver, and lung and localized to the cytoplasm and nucleus.

Applications

  • Application: IHC ; WB ; EM (EM) ; DB ; FACS

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Strickland et al. 1990. J Biol Chem. 265(29):17401-4. PMID: 1698775.
  • Sequence identity between the alpha 2-macroglobulin receptor and low density lipoprotein receptor-related protein suggests that this molecule is a multiFn receptor.