Cat. #151129
Anti-Leu2 [M236]
Cat. #: 151129
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: Leu2 (CD8)
Class: Monoclonal
Application: IHC ; IP ; RIA
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Walter Bodmer
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Leu2 [M236]
- Alternate name: Integrin Subunit Alpha 2; Alpha 2 Subunit Of VLA-2 Receptor; Platelet Membrane Glycoprotein Ia; CD49 Antigen-Like Family Member B; Collagen Receptor; CD49B; GPIa; Very Late Activation Protein 2 Receptor, Alpha-2 Subunit; Human Platelet Alloantigen System 5; Platelet Glycoprotein GPIa; Platelet Antigen Br; VLA-2 Subunit Alpha; CD49b Antigen; HPA-5; VLA-2; VLAA2; BR
- Research fields: Immunology;Stem cell biology
- Clone: M236
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 32 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: IHC ; IP ; RIA
- Description: M236 is useful for the identification of cytotoxic/suppressor cell subpopulation in peripheral blood, elimination of cytotoxic/suppressor cell subpopulation from peripheral blood and bone marrow, elimination of some T cell leukaemias and blocking of cytotoxic activity.
- Immunogen: MOLT 4 cell line.
- Isotype: IgG1
- Myeloma used: P3/NS1/1-Ag4.1
- Recommended controls: human platelets and megakaryocytes
Target Details
- Target: Leu2 (CD8)
- Molecular weight: 32 kDa
- Tissue cell line specificity: human platelets and megakaryocytes
- Target background: Leu-2 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells.
Applications
- Application: IHC ; IP ; RIA
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- 1st International Workshop on Human Leucocyte Differentiation Antigans (code T67), Paris, November 1982
