#151179

Anti-L1CAM [UJ181.4]

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Cat. #151179

Anti-L1CAM [UJ181.4]

Cat. #: 151179

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: L1 cell adhesion molecule (L1CAM; CD171)

Class: Monoclonal

Application: IHC ; IP ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: John Kemshead

Institute: Institute of Child Health

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-L1CAM [UJ181.4]
  • Research fields: Cell biology;Cell signaling and signal transduction;Neurobiology
  • Clone: UJ181.4
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 220-240 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC ; IP ; WB
  • Description: Used in diagnosis of primitive neuroectodermal tumours. Binds to tumours of neural and glial origin and does not bind to paediatric or adult brain. Used for bone marrow purging and intrathecal targeting
  • Immunogen: 16 week human foetal brain.
  • Isotype: IgG1
  • Myeloma used: P3X63Ag8.653

Target Details

  • Target: L1 cell adhesion molecule (L1CAM; CD171)
  • Molecular weight: 220-240 kDa
  • Target background: Used in diagnosis of primitive neuroectodermal tumours. Binds to tumours of neural and glial origin and does not bind to paediatric or adult brain. Used for bone marrow purging and intrathecal targeting

Applications

  • Application: IHC ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Garson.JA. 1983. MD Thesis. Birmingham
  • Bourne et al. 1989. Hybridoma. 8(4):415-26. PMID: 2550359.
  • Monoclonal antibodies M340 and UJ181.4 recognize antigens associated with primitive neuroectodermal tumours/tissues.
  • Coakham et al. 1985. J Clin Pathol. 38(2):165-73. PMID: 3881481.
  • Immunohistological diagnosis of central nervous system tumours using a monoclonal antibody panel.
  • Kemshead et al. 1983. Int J Cancer. 31(2):187-95. PMID: 6826247.
  • Monoclonal antibody UJ 127:11 detects a 220,000-240,000 kdal. glycoprotein present on a sub-set of neuroectodermally derived cells.