Cat. #156506
Anti-Human Ataxin-3 [4B8]
Cat. #: 156506
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Ataxin-3
Class: Monoclonal
Application: ELISA ; IP
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Patrick Loll
Institute: Drexel University
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Human Ataxin-3 [4B8]
- Alternate name: Machado-Joseph Disease (MJD) Protein 1; Spinocerebellar Ataxia Type 3
- Research fields: Biochemistry;Neurobiology
- Tool sub type: Primary antibody
- Class: Monoclonal
- Purpose: Marker
- Conjugation: Unconjugated
- Cell signalling pathway: PI3K signalling
- Molecular weight: 42 kDa
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; IP
- Description: Ataxin-3 is a deubiquitinating enzyme involved in the clearance of misfolded proteins. The enzyme functions in proteasome degradation and autophagy. Mutated forms of Ataxin-3 can lead to misfolded protein aggregation which cause the neurodegenerative disorder spinocerebellar ataxia type-3 (SCA3), also known as Machado-Joseph disease.
- Immunogen: Recombinant Human Ataxin-3
- Immunogen uniprot id: ATX3_HUMAN
- Recommended controls: IgG1 kappa
Target Details
- Target: Ataxin-3
- Molecular weight: 42 kDa
- Tissue cell line specificity: Mouse
- Target background: Ataxin-3 is a deubiquitinating enzyme involved in the clearance of misfolded proteins. The enzyme functions in proteasome degradation and autophagy. Mutated forms of Ataxin-3 can lead to misfolded protein aggregation which cause the neurodegenerative disorder spinocerebellar ataxia type-3 (SCA3), also known as Machado-Joseph disease.
Applications
- Application: ELISA ; IP
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
