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#162215

Anti-HSPB4 PAb

Cat. #162215

Anti-HSPB4 PAb

Cat. #: 162215

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: HSPB4

Class: Polyclonal

Application: WB ; IHC

Reactivity: Human, rat

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Roy Quinlan

Institute: University of Durham

Primary Citation: Sandilands A, et al. 2002. EMBO J. 15;21(22):6005-14. PMID: 12426373.

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-HSPB4 PAb
  • Alternate name: Alpha-crystallin A chain, CRYA1,CRYAA
  • Research fields: Cell biology
  • Tool sub type: Primary antibody
  • Class: Polyclonal
  • Conjugation: Unconjugated
  • Molecular weight: 22kDa, 173 residues
  • Reactivity: Human, rat
  • Application: WB ; IHC
  • Description: A polyclonal antibody for HSPB4 also known as Alpha-crystallin A chain or CRYAA. This target is a major lens structural protein, which has shown increased expression in retinoblastoma as compared to healthy retina. It acts as a molecular chaperone and anti-apoptotic regulator. This HSPB4 antibody recognises an epitope in the N-terminal of the protein. Antibody functions after aldehydye fixation.
  • Immunogen: peptide crosslinked to KLH
  • Isotype: IgG

Target Details

  • Target: HSPB4
  • Target alternate names: Alpha-crystallin A chain, CRYA1,CRYAA
  • Molecular weight: 22kDa, 173 residues
  • Target background: HSPB4 is also known as Alpha-crystallin A chain, it is a lens crystallin. It contributes to the transparency and refractive index of the lens. Alpha crystallins can act as molecular chaperones.

Applications

  • Application: WB ; IHC

Handling

  • Format: Liquid
  • Concentration: 1mg/ml
  • Unit size: 100 ug
  • Storage buffer: Serum plus azide (0.02%)
  • Storage conditions: -80° C
  • Shipping conditions: Dry ice

References

  • Naru J, et al. 2017. J Proteomics. 21
  • 159:77-91. PMID: 28232133.
  • Sandilands A, et al. 2002. EMBO J. 15
  • 21(22):6005-14. PMID: 12426373.

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