Cat. #152655
Anti-HA (H5N1) [1D10]
Cat. #: 152655
Unit size: 100 ug
Target: tEH5 (32.5kDa) protein, receptor binding domain of influenza hemagglutinin (H5)
Class: Monoclonal
Application: IF ; WB
Reactivity: Virus
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: A*STAR Accelerate Technologies Pte Ltd
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-HA (H5N1) [1D10]
- Research fields: Microbiology
- Clone: 1D10
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Virus
- Host: Mouse
- Application: IF ; WB
- Description: The hemagglutinin (HA) protein is one of the two major surface glycoproteins on the envelope of influenza A virus. The HA protein is responsible for receptor binding to host cells and for viral entry and is therefore the primary target of neutralizing antibodies. It is a homotrimer, with each subunit made up of two disulfide-linked polypeptides, HA1 and HA2. The N-terminal subunit HA1 contains the receptor binding domain. In this study, the receptor binding domain of the H5N1 avian influenza hemagglutinin (H5) was expressed in E.coli and used as antigen target. This project targets to generate monoclonal antibodies against H5 for diagnostic and therapeutic applications.
- Immunogen: 32.5kDa truncated H5 protein
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
- Recommended controls: Transfected cell lysates
Target Details
- Target: tEH5 (32.5kDa) protein, receptor binding domain of influenza hemagglutinin (H5)
- Target background: The hemagglutinin (HA) protein is one of the two major surface glycoproteins on the envelope of influenza A virus. The HA protein is responsible for receptor binding to host cells and for viral entry and is therefore the primary target of neutralizing antibodies. It is a homotrimer, with each subunit made up of two disulfide-linked polypeptides, HA1 and HA2. The N-terminal subunit HA1 contains the receptor binding domain. In this study, the receptor binding domain of the H5N1 avian influenza hemagglutinin (H5) was expressed in E.coli and used as antigen target. This project targets to generate monoclonal antibodies against H5 for diagnostic and therapeutic applications.
Applications
- Application: IF ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
