Cat. #151532
Anti-Factor VII [RFF-VII/2]
Cat. #: 151532
Unit size: 100 ug
Availability: 10-12 weeks
Target: Factor VII
Class: Monoclonal
Application: ELISA ; Fn ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Alison Goodall
Institute: University College London (UCL)
Tool Details
*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)
- Name: Anti-Factor VII [RFF-VII/2]
- Research fields: Tissue-specific biology
- Clone: RFF-VII/2
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: ELISA ; Fn ; WB
- Description: Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesised in the liver. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa via cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts prothrombin to thrombin. This monoclonal antibody inhibits human FVII activity and may also be used to immunodeplete FVII from normal plasma.
- Immunogen: Purified human Factor VII
- Isotype: IgG1 kappa
- Myeloma used: P3/NS1/1-Ag4.1
Target Details
- Target: Factor VII
- Target background: Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesised in the liver. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa via cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts prothrombin to thrombin. This monoclonal antibody inhibits human FVII activity and may also be used to immunodeplete FVII from normal plasma.
Applications
- Application: ELISA ; Fn ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1mg/ml
- Unit size: 100 ug
- Storage buffer: RPMI + 10% FCS; non-adherent; subculture every 2-3 days; split 1:5
- Storage conditions: -15° C to -25° C
- Shipping conditions: Dry ice
References
- Takase T et al. 1988. J Clin Pathol. 41(3):337-41. PMID: 3360957 Takase T et al. 1988. J Clin Pathol. 41(3):342-5. PMID: 3360958
