Skip to main content

#153631

Anti-Estrogen Receptor Beta1 [PPG5/10]

Cat. #153631

Anti-Estrogen Receptor Beta1 [PPG5/10]

Cat. #: 153631

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: Estrogen Receptor ?1

Class: Monoclonal

Application: IHC ; IF ; WB

Reactivity: Human ; Pig ; Primate ; Rat ; Sheep ; Rhesus macaque ; Cynomolgus monkey ; Turtle ; Goose

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: BioServ UK Ltd

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY (for other uses, please contact the licensing team)

  • Name: Anti-Estrogen Receptor Beta1 [PPG5/10]
  • Alternate name: Estrogen receptor beta, ER-beta, Nuclear receptor subfamily 3 group A member 2
  • Cancer: Breast cancer;Gynaecologic cancer
  • Cancers detailed: Breast cancer;Broadly Applicable;Ovarian
  • Research fields: Cancer;Immunology;Neurobiology
  • Clone: PPG5/10
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 59 kDa
  • Strain: Balb/c
  • Reactivity: Human ; Pig ; Primate ; Rat ; Sheep ; Rhesus macaque ; Cynomolgus monkey ; Turtle ; Goose
  • Host: Mouse
  • Application: IHC ; IF ; WB
  • Description: Estrogen receptors are commonly over-expressed in cancers. Clone PPG5/10 recognizes Estrogen Receptor Beta (ERÎ?) 1 and is useful in determining the expression of ERÎ?1 in cancer cells, mainly via immunohistochemistry.
  • Immunogen: Synthetic peptide CEDSKSKEGSQNPQSQ derived from the C terminus of human ER?1
  • Isotype: IgG2a
  • Myeloma used: Sp2/0-Ag14
  • Recommended controls: Ovary

Target Details

  • Target: Estrogen Receptor ?1
  • Molecular weight: 59 kDa
  • Tissue cell line specificity: Ovary
  • Target background: Estrogen receptors are commonly over-expressed in cancers. Clone PPG5/10 recognizes Estrogen Receptor Beta (ER?) 1 and is useful in determining the expression of ER?1 in cancer cells, mainly via immunohistochemistry.

Applications

  • Application: IHC ; IF ; WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Dry ice

References

  • Zannoni et al. 2016. Histopathology. 68(4):541-8. PMID: 26132417.
  • Sexual dimorphism in medulloblastoma features.
  • Gender effect in experimental models of human medulloblastoma: does the estrogen receptor ? signaling play a role?
  • Ciucci et al. 2014. PLoS One. 9(7):e101623. PMID: 25000562.
  • Asgari et al. 2011. Diagn Pathol. 6:61. PMID: 21733187.
  • Estrogen receptor beta expression in prostate adenocarcinoma.
  • Collins et al. 2009. BMC Cancer. 9:330. PMID: 19758455.
  • Expression of oestrogen receptors, ERalpha, ERbeta, and ERbeta variants, in endometrial cancers and evidence that prostaglandin F may play a role in regulating expression of ERalpha.
  • Schiessl et al. 2005. J Histochem Cytochem. 53(12):1441-9. PMID: 15983116.
  • Wong et al. 2005. J Pathol. 207(1):53-60. PMID: 15954165.
  • ERbeta isoform expression in colorectal carcinoma: an in vivo and in vitro study of clinicopathological and molecular correlates.
  • Expression of endothelial NO synthase, inducible NO synthase, and estrogen receptors alpha and beta in placental tissue of normal, preeclamptic, and intrauterine growth-restricted pregnancies.
  • Sierens et al. 2004. J Mol Endocrinol. 32(3):703-18. PMID: 15171710.
  • Cloning of oestrogen receptor beta from Old and New World primates: identification of splice variants and Fn analysis.
  • Torlakovic et al. 2002. Hum Pathol. 33(6):646-51. PMID: 12152165.
  • Prostate carcinoma expression of estrogen receptor-beta as detected by PPG5/10 antibody has positive association with primary Gleason grade and Gleason score.

Tool enquiry

Please ensure you use your organisation email address rather than personal where possible, as this helps us locate your organisation in our system faster.

Please note we may take up to three days to respond to your enquiry.

CancerTools.org uses the contact information provided to respond to you about our research tools and service. For more information please review our privacy policy.